Assessment of the effects of an aqueous extract of the leaves, flowers, and seeds of Crotalaria retusa L (Fabaceae) on the glycemia in rats

The aim of this study was to evaluate the effects an aqueous extract Crotalaria retusa L (Fabaceae) (EACr) on glycemia in Wistar rats, contribute valorization plants used traditional medicine for improvement people’s health. A phytochemical screening and pharmacological were carried out. administration substances animals made orally. qualitative out with leaves, flowers, pods highlight presence polyphenols, flavonoids, catechic, gallic tannins, quinonic compounds, alkaloids, sterols, polyterpenes. This showed hypoglycemic activity normoglycemic animals, treated dose 1000 mg/kg BW a percentage reduction 21.04%. After overload glucose, EACr (1000 BW) glibenclamide (10-2g/kg better antihyperglycemic rats post-treated, respective percentages 41.90 50.39%. has properties which would be probably related flavonoids. These generally recognized their effects, confer similar those certain insulin-secretors. results support use plant treatment diabetes bring scientific base.